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RGS11 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

NCBI Gene ID

8786

Swiss Prot

O94810

Accession Number

O94810

Host

Rabbit

Reactivity

Human

Immunogen

This RGS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human RGS11.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RGS11

NCBI Official Name

Regulator of G-protein signaling 11

NCBI Organism

Homo sapiens

Background Reference 01

Wang, J., et al. Carcinogenesis 31 (10) :1755-1761 (2010)

Background Reference 02

Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)

Background Reference 03

Saleem, Y., et al. Biochem. Biophys. Res. Commun. 386 (1) :65-70 (2009)

Background Reference 04

Martin, J., et al. Nature 432 (7020) :988-994 (2004)

Other Product Names

Regulator of G-protein signaling 11, RGS11, RGS11

Tested Applications

WB

Physical Properties

Liquid

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