PAX2 Antibody
Product Specifications
Background
PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
NCBI Gene ID
5076
Swiss Prot
Q02962
Accession Number
Q02962
Host
Rabbit
Reactivity
Human
Immunogen
This PAX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human PAX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PAX2
NCBI Official Name
Paired box protein Pax-2
NCBI Organism
Homo sapiens
Background Reference 01
Monte, N.M., et al. Cancer Res. 70 (15) :6225-6232 (2010)
Background Reference 02
Ozcan, A., et al. Arch. Pathol. Lab. Med. 134 (8) :1121-1129 (2010)
Background Reference 03
Quick, C.M., et al. Hum. Pathol. 41 (8) :1145-1149 (2010)
Background Reference 04
Martinovic-Bouriel, J., et al. Am. J. Med. Genet.152A (4), 830-835 (2010) :
Other Product Names
Paired box protein Pax-2, PAX2
Tested Applications
WB
Protein ID
223590261
Physical Properties
Liquid
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