IL23R Antibody
Product Specifications
Background
The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
NCBI Gene ID
149233
Swiss Prot
Q5VWK5
Accession Number
Q5VWK5
Host
Rabbit
Reactivity
Human
Immunogen
This IL23R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the C-terminal region of human IL23R.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
72 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
IL23R
NCBI Official Name
Interleukin-23 receptor
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Chen, J., et al. Mol. Carcinog. 49 (10) :862-868 (2010)
Background Reference 03
Mizuki, N., et al. Nat. Genet. 42 (8) :703-706 (2010)
Background Reference 04
Remmers, E.F., et al. Nat. Genet. 42 (8) :698-702 (2010)
Other Product Names
Interleukin-23 receptor, IL-23 receptor, IL-23R, IL23R
Tested Applications
WB
Protein ID
311033431
Physical Properties
Liquid
Frequently Asked Questions
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