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IL23R Antibody

Product Specifications

Background

The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

NCBI Gene ID

149233

Swiss Prot

Q5VWK5

Accession Number

Q5VWK5

Host

Rabbit

Reactivity

Human

Immunogen

This IL23R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the C-terminal region of human IL23R.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-876

Calculated Molecular Weight

72 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

IL23R

NCBI Official Name

Interleukin-23 receptor

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Chen, J., et al. Mol. Carcinog. 49 (10) :862-868 (2010)

Background Reference 03

Mizuki, N., et al. Nat. Genet. 42 (8) :703-706 (2010)

Background Reference 04

Remmers, E.F., et al. Nat. Genet. 42 (8) :698-702 (2010)

Other Product Names

Interleukin-23 receptor, IL-23 receptor, IL-23R, IL23R

Tested Applications

WB

Protein ID

311033431

Physical Properties

Liquid

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