CSRP3 Antibody
Product Specifications
Background
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
NCBI Gene ID
8048
Swiss Prot
P50461
Accession Number
P50461
Host
Rabbit
Reactivity
Human
Immunogen
This CSRP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the Central region of human CSRP3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-868
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CSRP3
NCBI Official Name
Cysteine and glycine-rich protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Zimmerman, R.S., et al. Genet. Med. 12 (5) :268-278 (2010)
Background Reference 03
Rampersaud, E., et al. Ann. Hum. Genet. 74 (2) :110-116 (2010)
Background Reference 04
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Other Product Names
Cysteine and glycine-rich protein 3, Cardiac LIM protein, Cysteine-rich protein 3, CRP3, LIM domain protein, cardiac, Muscle LIM protein, CSRP3, CLP, MLP
Tested Applications
WB
Protein ID
1705933
Physical Properties
Liquid
Curated Selection
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