HEYL Antibody

Product Specifications

Background

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH) -type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq].

NCBI Gene ID

26508

Swiss Prot

Q9NQ87

Accession Number

Q9NQ87

Host

Rabbit

Reactivity

Human

Immunogen

This HEYL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human HEYL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Symbol

HEYL

NCBI Official Name

Hairy/enhancer-of-split related with YRPW motif-like protein

NCBI Organism

Homo sapiens

Background Reference 01

Kokubo, H., et al. Trends Cardiovasc. Med. 15 (5) :190-194 (2005)

Background Reference 02

Colland, F., et al. Genome Res. 14 (7) :1324-1332 (2004)

Background Reference 03

Iso, T., et al. J. Cell. Physiol. 194 (3) :237-255 (2003)

Background Reference 04

Nakagawa, O., et al. Proc. Natl. Acad. Sci. U.S.A. 97 (25) :13655-13660 (2000)

Other Product Names

Hairy/enhancer-of-split related with YRPW motif-like protein, hHeyL, Class B basic helix-loop-helix protein 33, bHLHb33, Hairy-related transcription factor 3, HRT-3, hHRT3, HEYL, BHLHB33, HRT3