PPP1CC Antibody

Product Specifications

Background

Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca (2+) /calmodulin dependent protein kinase II.

NCBI Gene ID

5501

Swiss Prot

P36873

Accession Number

P36873

Host

Rabbit

Reactivity

Human

Immunogen

This PPP1CC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-309 amino acids from the C-terminal region of human PPP1CC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPP1CC

NCBI Official Name

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

NCBI Organism

Homo sapiens

Background Reference 01

Lee, J.H., et al. J. Biol. Chem. 285 (32) :24466-24476 (2010)

Background Reference 02

Kuzmin, A., et al. Biol. Reprod. 81 (2) :319-326 (2009)

Background Reference 03

Fujiki, R., et al. Nature 459 (7245) :455-459 (2009)

Background Reference 04

Rogne, M., et al. Hum. Mol. Genet. 18 (5) :978-987 (2009)

Other Product Names

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, PP-1G, Protein phosphatase 1C catalytic subunit, PPP1CC

Tested Applications

Protein ID

548573

Physical Properties

Liquid

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