MS4A1 Antibody

Product Specifications

Background

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.

NCBI Gene ID

931

Swiss Prot

P11836

Accession Number

P11836

Host

Rabbit

Reactivity

Human

Immunogen

This MS4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-244 amino acids from the C-terminal region of human MS4A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MS4A1

NCBI Official Name

B-lymphocyte antigen CD20

NCBI Organism

Homo sapiens

Background Reference 01

Weber, M.S., et al. Ann. Neurol. 68 (3) :369-383 (2010)

Background Reference 02

Wu, D., et al. Am. J. Clin. Pathol. 134 (2) :258-265 (2010)

Background Reference 03

De Haij, S., et al. Cancer Res. 70 (8) :3209-3217 (2010)

Background Reference 04

Beers, S.A., et al. Semin. Hematol. 47 (2) :107-114 (2010)

Other Product Names

B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20