SRM Antibody

Product Specifications

Background

The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.

NCBI Gene ID

6723

Swiss Prot

P19623

Accession Number

P19623

Host

Rabbit

Reactivity

Human

Immunogen

This SRM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the Central region of human SRM.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SRM

NCBI Official Name

Spermidine synthase

NCBI Organism

Homo sapiens

Background Reference 01

Wu, H., et al. Biochemistry 46 (28) :8331-8339 (2007)

Background Reference 02

Nishikawa, Y., et al. Biochem. J. 321 (PT 2), 537-543 (1997) :

Background Reference 03

Lakanen, J.R., et al. J. Med. Chem. 38 (14) :2714-2727 (1995)

Background Reference 04

Kauppinen, L. FEBS Lett. 365 (1) :61-65 (1995)

Other Product Names

Spermidine synthase, SPDSY, Putrescine aminopropyltransferase, SRM, SPS1, SRML1

Tested Applications

Protein ID

134811

Physical Properties

Liquid

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