FKBP6 Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein may have cis-trans prolyl isomerase activity, and binds to clathrin heavy chain and heat shock protein 72. This gene is found to be deleted in Williams syndrome, and the orthologous gene in mouse is essential for fertility and homologous pairing in male meiosis.
NCBI Gene ID
8468
Swiss Prot
O75344
Accession Number
O75344
Host
Rabbit
Reactivity
Human
Immunogen
This FKBP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-284 amino acids from the C-terminal region of human FKBP6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
37 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FKBP6
NCBI Official Name
Inactive peptidyl-prolyl cis-trans isomerase FKBP6
NCBI Organism
Homo sapiens
Background Reference 01
Aston, K.I., et al. Hum. Reprod. 25 (6) :1383-1397 (2010)
Background Reference 02
Jarczowski, F., et al. J. Biol. Chem. 284 (2) :766-773 (2009)
Background Reference 03
Jarczowski, F., et al. Biochemistry 47 (26) :6946-6952 (2008)
Background Reference 04
Zhang, W., et al. Reproduction 133 (2) :511-516 (2007)
Other Product Names
Inactive peptidyl-prolyl cis-trans isomerase FKBP6, Inactive PPIase FKBP6, 36 kDa FK506-binding protein, 36 kDa FKBP, FKBP-36, FK506-binding protein 6, FKBP-6, Immunophilin FKBP36, FKBP6, FKBP36
Tested Applications
WB
Physical Properties
Liquid
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