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SH3BP1 Antibody

Product Specifications

Background

SH3BP1 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity) .

NCBI Gene ID

23616

Swiss Prot

Q9Y3L3

Accession Number

Q9Y3L3

Host

Rabbit

Reactivity

Human

Immunogen

This SH3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-446 amino acids from the Central region of human SH3BP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-823

Calculated Molecular Weight

76 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SH3BP1

NCBI Official Name

SH3 domain-binding protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Collins, J.E., et al. Genome Biol. (10), R84 (2004) :

Background Reference 02

Scott, M.P., et al. J. Biol. Chem. 277 (31) :28238-28246 (2002)

Background Reference 03

Dunham, I., et al. Nature 402 (6761) :489-495 (1999)

Other Product Names

SH3 domain-binding protein 1, 3BP-1, SH3BP1

Tested Applications

WB

Protein ID

51338841

Physical Properties

Liquid

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