SH3BP1 Antibody
Product Specifications
Background
SH3BP1 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity) .
NCBI Gene ID
23616
Swiss Prot
Q9Y3L3
Accession Number
Q9Y3L3
Host
Rabbit
Reactivity
Human
Immunogen
This SH3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-446 amino acids from the Central region of human SH3BP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
76 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SH3BP1
NCBI Official Name
SH3 domain-binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Collins, J.E., et al. Genome Biol. (10), R84 (2004) :
Background Reference 02
Scott, M.P., et al. J. Biol. Chem. 277 (31) :28238-28246 (2002)
Background Reference 03
Dunham, I., et al. Nature 402 (6761) :489-495 (1999)
Other Product Names
SH3 domain-binding protein 1, 3BP-1, SH3BP1
Tested Applications
WB
Protein ID
51338841
Physical Properties
Liquid
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