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MGAT1 Antibody

Product Specifications

Background

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene.

NCBI Gene ID

4245

Swiss Prot

P26572

Accession Number

P26572

Host

Rabbit

Reactivity

Human

Immunogen

This MGAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-187 amino acids from the Central region of human MGAT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-817

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MGAT1

NCBI Official Name

Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Henquet, M., et al. Transgenic Res. 19 (4) :535-547 (2010)

Background Reference 02

Johansson, A., et al. Obesity (Silver Spring) 18 (4) :803-808 (2010)

Background Reference 03

Bousman, C.A., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (8), 1025-1049 (2009) :

Background Reference 04

Lowe, J.K., et al. PLoS Genet. (2), E1000365 (2009) :

Other Product Names

Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, GNT-I, GlcNAc-T I, MGAT1, GGNT1, GLCT1, GLYT1, MGAT

Tested Applications

WB

Protein ID

311033399

Physical Properties

Liquid

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