PI4K2A Antibody

Product Specifications

Background

Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]) .

NCBI Gene ID

55361

Swiss Prot

Q9BTU6

Accession Number

Q9BTU6

Host

Rabbit

Reactivity

Human

Immunogen

This PI4K2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human PI4K2A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PI4K2A

NCBI Official Name

Phosphatidylinositol 4-kinase type 2-alpha

NCBI Organism

Homo sapiens

Background Reference 01

Li, J., et al. Oncogene 29 (17) :2550-2559 (2010)

Background Reference 02

Qin, Y., et al. J. Biol. Chem. 284 (34) :22544-22548 (2009)

Background Reference 03

Salazar, G., et al. J. Biol. Chem. 284 (3) :1790-1802 (2009)

Background Reference 04

Craige, B., et al. Mol. Biol. Cell 19 (4) :1415-1426 (2008)

Other Product Names

Phosphatidylinositol 4-kinase type 2-alpha, Phosphatidylinositol 4-kinase type II-alpha, PI4K2A

Tested Applications

Protein ID

74752344

Physical Properties

Liquid

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