GPLD1 Antibody

Product Specifications

Background

Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane.

NCBI Gene ID

2822

Swiss Prot

P80108

Accession Number

P80108

Host

Rabbit

Reactivity

Human

Immunogen

This GPLD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-306 amino acids from the Central region of human GPLD1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

92 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GPLD1

NCBI Official Name

Phosphatidylinositol-glycan-specific phospholipase D

NCBI Organism

Homo sapiens

Background Reference 01

Speliotes, E.K., et al. Hepatology 52 (3) :904-912 (2010)

Background Reference 02

Tang, J.H., et al. Clin. Biochem. 42 (4-5), 400-407 (2009) :

Background Reference 03

Yuan, X., et al. Am. J. Hum. Genet. 83 (4) :520-528 (2008)

Background Reference 04

Wright, M.H., et al. Biochem. Biophys. Res. Commun. 369 (2) :478-484 (2008)

Other Product Names

Phosphatidylinositol-glycan-specific phospholipase D, PI-G PLD, Glycoprotein phospholipase D, Glycosyl-phosphatidylinositol-specific phospholipase D, GPI-PLD, GPI-specific phospholipase D, GPLD1, PIGPLD1