POLS Antibody

Product Specifications

Background

The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described.

NCBI Gene ID

11044

Swiss Prot

Q5XG87

Accession Number

Q5XG87

Host

Rabbit

Reactivity

Human

Immunogen

This POLS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human POLS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

82 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PAPD7

NCBI Official Name

Non-canonical poly (A) RNA polymerase PAPD7

NCBI Organism

Homo sapiens

Background Reference 01

Jarjanazi, H., et al. Hum. Mutat. 29 (4) :461-467 (2008)

Background Reference 02

Carson, D.R., et al. Proc. Natl. Acad. Sci. U.S.A. 98 (15) :8270-8275 (2001)

Background Reference 03

Wang, Z., et al. Science 289 (5480) :774-779 (2000)

Background Reference 04

Walowsky, C., et al. J. Biol. Chem. 274 (11) :7302-7308 (1999)

Other Product Names

Non-canonical poly (A) RNA polymerase PAPD7, DNA polymerase sigma, LAK-1, PAP-associated domain-containing protein 7, TRAMP-like complex polyadenylate polymerase, Terminal uridylyltransferase 5, TUTase 5, Topoisomerase-related function protein 4-1, TRF4-1, PAPD7, POLS, TRF4