TSFM Antibody

Product Specifications

Background

This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.

NCBI Gene ID

10102

Swiss Prot

P43897

Accession Number

P43897

Host

Rabbit

Reactivity

Human

Immunogen

This TSFM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the C-terminal region of human TSFM.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TSFM

NCBI Official Name

Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135}

NCBI Organism

Homo sapiens

Background Reference 01

Wang, W., et al. Nucleic Acids Res. (2010) In press :

Background Reference 02

Smeitink, J.A., et al. Am. J. Hum. Genet. 79 (5) :869-877 (2006)

Background Reference 03

Antonicka, H., et al. Hum. Mol. Genet. 15 (11) :1835-1846 (2006)

Background Reference 04

Vernon, J.L., et al. Cytogenet. Cell Genet. 89 (3-4), 145-146 (2000) :

Other Product Names

Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135}, EF-Ts {ECO:0000255|HAMAP-Rule:MF_03135}, EF-TsMt {ECO:0000255|HAMAP-Rule:MF_03135}, TSFM {ECO:0000255|HAMAP-Rule:MF_03135}