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NHLH1 Antibody

Product Specifications

Background

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040) .[supplied by OMIM].

NCBI Gene ID

4807

Swiss Prot

Q02575

Accession Number

Q02575

Host

Rabbit

Reactivity

Human

Immunogen

This NHLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the Central region of human NHLH1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

15 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NHLH1

NCBI Official Name

Helix-loop-helix protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Manetopoulos, C., et al. Biochem. Biophys. Res. Commun. 307 (4) :891-899 (2003)

Background Reference 02

Bao, J., et al. Development 127 (2) :425-435 (2000)

Background Reference 03

Lipkowitz, S., et al. J. Biol. Chem. 267 (29) :21065-21071 (1992)

Background Reference 04

Brown, L., et al. Proc. Natl. Acad. Sci. U.S.A. 89 (18) :8492-8496 (1992)

Other Product Names

Helix-loop-helix protein 1, HEN-1, Class A basic helix-loop-helix protein 35, bHLHa35, Nescient helix loop helix 1, NSCL-1, NHLH1, BHLHA35, HEN1

Tested Applications

WB

Protein ID

399885

Physical Properties

Liquid

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