UBA6 Antibody

Product Specifications

Background

Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3) . UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]) .

NCBI Gene ID

55236

Swiss Prot

A0AVT1

Accession Number

A0AVT1

Host

Rabbit

Reactivity

Human

Immunogen

This UBA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 861-889 amino acids from the C-terminal region of human UBA6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

118 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UBA6

NCBI Official Name

Ubiquitin-like modifier-activating enzyme 6

NCBI Organism

Homo sapiens

Background Reference 01

Groettrup, M., et al. Trends Biochem. Sci. 33 (5) :230-237 (2008)

Background Reference 02

Chiu, Y.H., et al. Mol. Cell 27 (6) :1014-1023 (2007)

Background Reference 03

Pelzer, C., et al. J. Biol. Chem. 282 (32) :23010-23014 (2007)

Background Reference 04

Jin, J., et al. Nature 447 (7148) :1135-1138 (2007)

Other Product Names

Ubiquitin-like modifier-activating enzyme 6, Ubiquitin-activating enzyme 6, Monocyte protein 4, MOP-4, Ubiquitin-activating enzyme E1-like protein 2, E1-L2, UBA6, MOP4, UBE1L2