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WTAP Antibody

Product Specifications

Background

The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in three transcript variants, two of which encode the same isoform.

NCBI Gene ID

9589

Swiss Prot

Q15007

Accession Number

Q15007

Host

Rabbit

Reactivity

Human

Immunogen

This WTAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human WTAP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-781

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

WTAP

NCBI Official Name

Pre-mRNA-splicing regulator WTAP

NCBI Organism

Homo sapiens

Background Reference 01

Su, J., et al. Diabetes Res. Clin. Pract. 87 (2) :167-175 (2010)

Background Reference 02

Small, T.W., et al. J. Biol. Chem. 284 (37) :24684-24695 (2009)

Background Reference 03

Benyamin, B., et al. Am. J. Hum. Genet. 84 (1) :60-65 (2009)

Background Reference 04

Zhong, S., et al. Plant Cell 20 (5) :1278-1288 (2008)

Other Product Names

Pre-mRNA-splicing regulator WTAP, Female-lethal (2) D homolog, hFL (2) D, WT1-associated protein, Wilms tumor 1-associating protein, WTAP, KIAA0105

Tested Applications

WB

Protein ID

47117889

Physical Properties

Liquid

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