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HPS3 Antibody

Product Specifications

Background

This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined. [provided by RefSeq].

NCBI Gene ID

84343

Swiss Prot

Q969F9

Accession Number

Q969F9

Host

Rabbit

Reactivity

Human

Immunogen

This HPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the N-terminal region of human HPS3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-778

Calculated Molecular Weight

114 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HPS3

NCBI Official Name

Hermansky-Pudlak syndrome 3 protein

NCBI Organism

Homo sapiens

Background Reference 01

Torres-Serrant, M., et al. J. Pediatr. Hematol. Oncol. 32 (6) :448-453 (2010)

Background Reference 02

Huizing, M., et al. Platelets 18 (2) :150-157 (2007)

Background Reference 03

Santiago Borrero, P.J., et al. J. Invest. Dermatol. 126 (1) :85-90 (2006)

Background Reference 04

Boissy, R.E., et al. Am. J. Pathol. 166 (1) :231-240 (2005)

Other Product Names

Hermansky-Pudlak syndrome 3 protein, HPS3

Tested Applications

WB

Protein ID

20532121

Physical Properties

Liquid

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