What is the catalog number for PCSK4 Antibody?

The catalog number for PCSK4 Antibody is 58-777.

What sizes are available for PCSK4 Antibody?

PCSK4 Antibody is available in the following size(s): 400 µL.

Is PCSK4 Antibody in stock?

PCSK4 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

PCSK4 Antibody

Product Specifications

Background

Proprotein convertases, including PCSK4, are calcium-dependent serine proteases related to bacterial subtilisins and to yeast kexin. These enzymes process precursor proteins to their active forms by selective cleavage of the polypeptide at sites following paired basic amino acids. In mammals, this family comprises PC1 (MIM 162150), PC2 (MIM 162151), PC4, PC5 (MIM 600488), furin (FUR; MIM 136950), and PACE4 (MIM 167405) . Substrates for these enzymes range from prohormones to precursors for growth factors to cell surface receptors and viral surface glycoproteins (Cao et al., 2001 [PubMed 11776387]) .[supplied by OMIM].

NCBI Gene ID

54760

Swiss Prot

Q6UW60

Accession Number

Q6UW60

Host

Rabbit

Reactivity

Human

Immunogen

This PCSK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the N-terminal region of human PCSK4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PCSK4

NCBI Official Name

Proprotein convertase subtilisin/kexin type 4

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 02

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 03

Batta, K., et al. J. Mol. Biol. 385 (3) :788-799 (2009)

Background Reference 04

Qiu, Q., et al. Proc. Natl. Acad. Sci. U.S.A. 102 (31) :11047-11052 (2005)

Other Product Names

Proprotein convertase subtilisin/kexin type 4, 3421-, Proprotein convertase 4, PC4, PCSK4 {ECO:0000312|EMBL:AAH363541}

Tested Applications

Protein ID

296439263

Physical Properties

Liquid

Frequently Asked Questions

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