TRPC7 Antibody

Product Specifications

Background

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity) . May also be activated by intracellular calcium store depletion.

NCBI Gene ID

57113

Swiss Prot

Q9HCX4

Accession Number

Q9HCX4

Host

Rabbit

Reactivity

Human

Immunogen

This TRPC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 834-862 amino acids from the C-terminal region of human TRPC7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

100 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TRPC7

NCBI Official Name

Short transient receptor potential channel 7

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 02

Miyagi, K., et al. J. Biol. Chem. 284 (49) :34400-34412 (2009)

Background Reference 03

Graubert, T.A., et al. PLoS ONE (2), E4583 (2009) :

Background Reference 04

Abed, E., et al. Cell Prolif. 40 (6) :849-865 (2007)

Other Product Names

Short transient receptor potential channel 7, TrpC7, Transient receptor protein 7, TRP-7, hTRP7, TRPC7, TRP7

Tested Applications

Protein ID

18202960

Physical Properties

Liquid

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