CCL7 Antibody

Product Specifications

Background

This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.

NCBI Gene ID

6354

Swiss Prot

P80098

Accession Number

P80098

Host

Rabbit

Reactivity

Human

Immunogen

This CCL7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the Central region of human CCL7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

11 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CCL7

NCBI Official Name

C-C motif chemokine 7

NCBI Organism

Homo sapiens

Background Reference 01

McGovern, D.P., et al. Hum. Mol. Genet. 19 (17) :3468-3476 (2010)

Background Reference 02

Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

Background Reference 03

Schuurhof, A., et al. Pediatr. Pulmonol. 45 (6) :608-613 (2010)

Background Reference 04

Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

Other Product Names

C-C motif chemokine 7, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, MCP-3, NC28, Small-inducible cytokine A7, CCL7, MCP3, SCYA6, SCYA7