PBXIP1 Antibody

Product Specifications

Background

Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.

NCBI Gene ID

57326

Swiss Prot

Q96AQ6

Accession Number

Q96AQ6

Host

Rabbit

Reactivity

Human

Immunogen

This PBXIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-501 amino acids from the C-terminal region of human PBXIP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

81 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PBXIP1

NCBI Official Name

Pre-B-cell leukemia transcription factor-interacting protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

Background Reference 02

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 03

Lim, J., et al. Cell 125 (4) :801-814 (2006)

Background Reference 04

Abramovich, C., et al. Oncogene 21 (44) :6766-6771 (2002)

Other Product Names

Pre-B-cell leukemia transcription factor-interacting protein 1, Hematopoietic PBX-interacting protein, PBXIP1, HPIP

Tested Applications

Protein ID

74751749

Physical Properties

Liquid

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