EXT1 Antibody

Product Specifications

Background

This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq].

NCBI Gene ID

2131

Swiss Prot

Q16394

Accession Number

Q16394

Host

Rabbit

Reactivity

Human

Immunogen

This EXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the Central region of human EXT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

86 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

EXT1

NCBI Official Name

Exostosin-1

NCBI Organism

Homo sapiens

Background Reference 01

Zuntini, M., et al. Oncogene 29 (26) :3827-3834 (2010)

Background Reference 02

Wen, W., et al. Genet Test Mol Biomarkers 14 (3) :371-376 (2010)

Background Reference 03

Li, Y., et al. Pathology 42 (1) :91-93 (2010)

Background Reference 04

Baasanjav, S., et al. BMC Med. Genet. 11, 110 (2010) :

Other Product Names

Exostosin-1, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 1, Putative tumor suppressor protein EXT1, EXT1