EXT1 Antibody
Product Specifications
Background
This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq].
NCBI Gene ID
2131
Swiss Prot
Q16394
Accession Number
Q16394
Host
Rabbit
Reactivity
Human
Immunogen
This EXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the Central region of human EXT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
86 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
EXT1
NCBI Official Name
Exostosin-1
NCBI Organism
Homo sapiens
Background Reference 01
Zuntini, M., et al. Oncogene 29 (26) :3827-3834 (2010)
Background Reference 02
Wen, W., et al. Genet Test Mol Biomarkers 14 (3) :371-376 (2010)
Background Reference 03
Li, Y., et al. Pathology 42 (1) :91-93 (2010)
Background Reference 04
Baasanjav, S., et al. BMC Med. Genet. 11, 110 (2010) :
Other Product Names
Exostosin-1, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 1, Putative tumor suppressor protein EXT1, EXT1
Tested Applications
WB
Protein ID
20141422
Physical Properties
Liquid
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