RCBTB1 Antibody

Product Specifications

Background

This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.

NCBI Gene ID

55213

Swiss Prot

Q8NDN9

Accession Number

Q8NDN9

Host

Rabbit

Reactivity

Human

Immunogen

This RCBTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-377 amino acids from the Central region of human RCBTB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RCBTB1

NCBI Official Name

RCC1 and BTB domain-containing protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Genuneit, J., et al. Clin. Exp. Allergy 39 (12) :1875-1888 (2009)

Background Reference 02

Guo, D.F., et al. J. Biol. Chem. 279 (20) :21109-21120 (2004)

Background Reference 03

Dunham, A., et al. Nature 428 (6982) :522-528 (2004)

Background Reference 04

Solomou, E.E., et al. Leuk. Lymphoma 44 (9) :1579-1585 (2003)

Other Product Names

RCC1 and BTB domain-containing protein 1, Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, Regulator of chromosome condensation and BTB domain-containing protein 1, RCBTB1, CLLD7, E45