RCBTB1 Antibody
Product Specifications
Background
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.
NCBI Gene ID
55213
Swiss Prot
Q8NDN9
Accession Number
Q8NDN9
Host
Rabbit
Reactivity
Human
Immunogen
This RCBTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-377 amino acids from the Central region of human RCBTB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-739
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RCBTB1
NCBI Official Name
RCC1 and BTB domain-containing protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Genuneit, J., et al. Clin. Exp. Allergy 39 (12) :1875-1888 (2009)
Background Reference 02
Guo, D.F., et al. J. Biol. Chem. 279 (20) :21109-21120 (2004)
Background Reference 03
Dunham, A., et al. Nature 428 (6982) :522-528 (2004)
Background Reference 04
Solomou, E.E., et al. Leuk. Lymphoma 44 (9) :1579-1585 (2003)
Other Product Names
RCC1 and BTB domain-containing protein 1, Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, Regulator of chromosome condensation and BTB domain-containing protein 1, RCBTB1, CLLD7, E45
Tested Applications
WB
Protein ID
74751227
Physical Properties
Liquid
Curated Selection
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