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OBFC1 Antibody

Product Specifications

Background

OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 [PubMed 19119139]) . OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM 613130) (Miyake et al., 2009 [PubMed 19854130]) .

NCBI Gene ID

79991

Swiss Prot

Q9H668

Accession Number

Q9H668

Host

Rabbit

Reactivity

Human

Immunogen

This OBFC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the C-terminal region of human OBFC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

OBFC1

NCBI Official Name

CST complex subunit STN1

NCBI Organism

Homo sapiens

Background Reference 01

Levy, D., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (20) :9293-9298 (2010)

Background Reference 02

Miyake, Y., et al. Mol. Cell 36 (2) :193-206 (2009)

Background Reference 03

Wan, M., et al. J. Biol. Chem. 284 (39) :26725-26731 (2009)

Background Reference 04

Casteel, D.E., et al. J. Biol. Chem. 284 (9) :5807-5818 (2009)

Other Product Names

CST complex subunit STN1, Oligonucleotide/oligosaccharide-binding fold-containing protein 1, Suppressor of cdc thirteen homolog, OBFC1, STN1

Tested Applications

WB

Protein ID

62900737

Physical Properties

Liquid

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