GGPS1 Antibody
Product Specifications
Background
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq].
NCBI Gene ID
9453
Swiss Prot
O95749
Accession Number
O95749
Host
Rabbit
Reactivity
Human
Immunogen
This GGPS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-202 amino acids from the Central region of human GGPS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GGPS1
NCBI Official Name
Geranylgeranyl pyrophosphate synthase
NCBI Organism
Homo sapiens
Background Reference 01
Choi, H.J., et al. Yonsei Med. J. 51 (2) :231-238 (2010)
Background Reference 02
Raz, T., et al. Blood 110 (6) :2102-2109 (2007)
Background Reference 03
Miyagi, Y., et al. J. Biochem. 142 (3) :377-381 (2007)
Background Reference 04
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Other Product Names
Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, 251-, (2E,6E) -farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, GGPS1
Tested Applications
WB
Physical Properties
Liquid
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