What is the catalog number for UBE2D3 Antibody?

The catalog number for UBE2D3 Antibody is 58-731.

What sizes are available for UBE2D3 Antibody?

UBE2D3 Antibody is available in the following size(s): 400 µL.

Is UBE2D3 Antibody in stock?

UBE2D3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

UBE2D3 Antibody

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

NCBI Gene ID

7323

Swiss Prot

P61077

Accession Number

P61077

Host

Rabbit

Reactivity

Human

Immunogen

This UBE2D3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-136 amino acids from the C-terminal region of human UBE2D3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig, Bovine, Monkey, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

17 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UBE2D3

NCBI Official Name

Ubiquitin-conjugating enzyme E2 D3

NCBI Organism

Homo sapiens

Background Reference 01

Kalsi, G., et al. Hum. Mol. Genet. 19 (12) :2497-2506 (2010)

Background Reference 02

Wu, K., et al. Mol. Cell 37 (6) :784-796 (2010)

Background Reference 03

Vina-Vilaseca, A., et al. J. Biol. Chem. 285 (10) :7645-7656 (2010)

Background Reference 04

Markson, G., et al. Genome Res. 19 (10) :1905-1911 (2009)

Other Product Names

Ubiquitin-conjugating enzyme E2 D3, Ubiquitin carrier protein D3, Ubiquitin-conjugating enzyme E2 (17) KB 3, Ubiquitin-conjugating enzyme E2-17 kDa 3, Ubiquitin-protein ligase D3, UBE2D3, UBC5C, UBCH5C