P2RX1 Antibody

Product Specifications

Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

NCBI Gene ID

5023

Swiss Prot

P51575

Accession Number

P51575

Host

Rabbit

Reactivity

Human

Immunogen

This P2RX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-372 amino acids from the C-terminal region of human P2RX1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

P2RX1

NCBI Official Name

P2X purinoceptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Allsopp, R.C., et al. J. Biol. Chem. 285 (43) :32770-32777 (2010)

Background Reference 02

Harper, M.T., et al. J. Thromb. Haemost. 8 (7) :1604-1613 (2010)

Background Reference 03

Lalo, U., et al. J. Neurochem. 113 (5) :1177-1187 (2010)

Background Reference 04

Varani, K., et al. Cell. Physiol. Biochem. 25 (2-3), 325-336 (2010) :

Other Product Names

P2X purinoceptor 1, P2X1, ATP receptor, Purinergic receptor, P2RX1, P2X1

Tested Applications

Protein ID

1709519

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E51A09231 100 µL

Granulin Antibody

Ask

View Details

MF-0124006-01 10 mg

Oganomycin A

Ask

View Details

MF-0124006-02 50 mg

Oganomycin A

Ask

View Details

243807-APC 100 µL

BMP2 (Bone Morphogenetic Protein 2, BMP2A) (APC)

Ask

View Details

NBP2-80053AF647 0.1 mL

Rat Monoclonal Lymphotoxin beta R/TNFRSF3 Antibody (4H8 WH2) [Alexa Fluor 647]

Ask

View Details