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PER1 Antibody

Product Specifications

Background

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. Alternative splicing has been observed in this gene; however, these variants have not been fully described.

NCBI Gene ID

5187

Swiss Prot

O15534

Accession Number

O15534

Host

Rabbit

Reactivity

Human

Immunogen

This PER1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1156-1183 amino acids from the C-terminal region of human PER1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-728

Calculated Molecular Weight

136 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PER1

NCBI Official Name

Period circadian protein homolog 1

NCBI Organism

Homo sapiens

Background Reference 01

Xia, H.C., et al. CanNeurol Sci 37 (3) :365-370 (2010)

Background Reference 02

Soria, V., et al. Neuropsychopharmacology 35 (6) :1279-1289 (2010)

Background Reference 03

Utge, S.J., et al. PLoS ONE (2), E9259 (2010) :

Background Reference 04

Zhu, Y., et al. Cancer Res. 69 (24) :9315-9322 (2009)

Other Product Names

Period circadian protein homolog 1, hPER1, Circadian clock protein PERIOD 1, Circadian pacemaker protein Rigui, PER1, KIAA0482, PER, RIGUI

Tested Applications

WB

Physical Properties

Liquid

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