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ARL1 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs) . ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.

NCBI Gene ID

400

Swiss Prot

P40616

Accession Number

P40616

Host

Rabbit

Reactivity

Human

Immunogen

This ARL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the Central region of human ARL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-726

Calculated Molecular Weight

20 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ARL1

NCBI Official Name

ADP-ribosylation factor-like protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Houghton, F.J., et al. Cell 138 (4) :787-794 (2009)

Background Reference 02

Nishimoto-Morita, K., et al. J. Biol. Chem. 284 (16) :10583-10592 (2009)

Background Reference 03

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Background Reference 04

Zahn, C., et al. Mol. Membr. Biol. 23 (6) :475-485 (2006)

Other Product Names

ADP-ribosylation factor-like protein 1, ARL1

Tested Applications

WB

Protein ID

728888

Physical Properties

Liquid

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