SIT1 Antibody

Product Specifications

Background

Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells. Involved in positive selection of T-cells.

NCBI Gene ID

27240

Swiss Prot

Q9Y3P8

Accession Number

Q9Y3P8

Host

Rabbit

Reactivity

Human

Immunogen

This SIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the C-terminal region of human SIT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

21 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SIT1

NCBI Official Name

Signaling threshold-regulating transmembrane adapter 1

NCBI Organism

Homo sapiens

Background Reference 01

Chapuis, J., et al. Mol. Psychiatry 14 (11) :1004-1016 (2009)

Background Reference 02

Tedoldi, S., et al. Blood 107 (1) :213-221 (2006)

Background Reference 03

Tao, W.A., et al. Nat. Methods 2 (8) :591-598 (2005)

Background Reference 04

Tao, W.A., et al. Nat. Methods 2 (8) :591-598 (2005)

Other Product Names

Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembrane adapter protein, Suppression-inducing transmembrane adapter 1, gp30/40, SIT1, SIT