TRPV5 Antibody

Product Specifications

Background

This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.

NCBI Gene ID

56302

Swiss Prot

Q9NQA5

Accession Number

Q9NQA5

Host

Rabbit

Reactivity

Human

Immunogen

This TRPV5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 634-663 amino acids from the C-terminal region of human TRPV5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TRPV5

NCBI Official Name

Transient receptor potential cation channel subfamily V member 5

NCBI Organism

Homo sapiens

Background Reference 01

Chamoux, E., et al. J. Biol. Chem. 285 (33) :25354-25362 (2010)

Background Reference 02

Kennedy, B.G., et al. Mol. Vis. 16, 665-675 (2010) :

Background Reference 03

Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)

Background Reference 04

De Groot, T., et al. J. Am. Soc. Nephrol. 20 (8) :1693-1704 (2009)

Other Product Names

Transient receptor potential cation channel subfamily V member 5, TrpV5, Calcium transport protein 2, CaT2, Epithelial calcium channel 1, ECaC, ECaC1, Osm-9-like TRP channel 3, OTRPC3, TRPV5, ECAC1