PPIL1 Antibody

Product Specifications

Background

This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases) . The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

NCBI Gene ID

51645

Swiss Prot

Q9Y3C6

Accession Number

Q9Y3C6

Host

Rabbit

Reactivity

Human

Immunogen

This PPIL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human PPIL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

18 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPIL1

NCBI Official Name

Peptidyl-prolyl cis-trans isomerase-like 1

NCBI Organism

Homo sapiens

Background Reference 01

Wang, X., et al. J. Biol. Chem. 285 (7) :4951-4963 (2010)

Background Reference 02

Xu, C., et al. J. Biol. Chem. 281 (23) :15900-15908 (2006)

Background Reference 03

Xu, C., et al. J. Biomol. NMR 31 (2) :179-180 (2005)

Background Reference 04

Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)

Other Product Names

Peptidyl-prolyl cis-trans isomerase-like 1, PPIase, Rotamase PPIL1, PPIL1, CYPL1

Tested Applications

Protein ID

20177874

Physical Properties

Liquid

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