ZNRF1 Antibody

Product Specifications

Background

In a study identifying genes in rat that are upregulated in response to nerve damage, a gene which is highly expressed in ganglia and in the central nervous system was found. The protein encoded by the rat gene contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification. The protein encoded by this human gene is highly similar in sequence to that encoded by the rat gene. [provided by RefSeq].

NCBI Gene ID

84937

Swiss Prot

Q8ND25

Accession Number

Q8ND25

Host

Rabbit

Reactivity

Human

Immunogen

This ZNRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the Central region of human ZNRF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZNRF1

NCBI Official Name

E3 ubiquitin-protein ligase ZNRF1

NCBI Organism

Homo sapiens

Background Reference 01

Dastani, Z., et al. Eur. J. Hum. Genet. 18 (3) :342-347 (2010)

Background Reference 02

Yoshida, K., et al. Biochem. Biophys. Res. Commun. 389 (3) :506-511 (2009)

Background Reference 03

Markson, G., et al. Genome Res. 19 (10) :1905-1911 (2009)

Background Reference 04

Van Wijk, S.J., et al. Mol. Syst. Biol. 5, 295 (2009) :

Other Product Names

E3 ubiquitin-protein ligase ZNRF1, 632-, Nerve injury-induced gene 283 protein, Zinc/RING finger protein 1, ZNRF1, NIN283

Tested Applications

Protein ID

126253846

Physical Properties

Liquid

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