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RCN1 Antibody

Product Specifications

Background

Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca (+2) -binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.

NCBI Gene ID

5954

Swiss Prot

Q15293

Accession Number

Q15293

Host

Rabbit

Reactivity

Human

Immunogen

This RCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-331 amino acids from the C-terminal region of human RCN1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RCN1

NCBI Official Name

Reticulocalbin-1

NCBI Organism

Homo sapiens

Background Reference 01

Favor, J., et al. Genetics 182 (4) :1077-1088 (2009)

Background Reference 02

Hansen, G.A., et al. Mol. Cell. Biochem. 320 (1-2), 25-33 (2009) :

Background Reference 03

Cooper, C.R., et al. J. Cell. Biochem. 104 (6) :2298-2309 (2008)

Background Reference 04

Lim, J., et al. Cell 125 (4) :801-814 (2006)

Other Product Names

Reticulocalbin-1, RCN1, RCN

Tested Applications

WB

Protein ID

2493462

Physical Properties

Liquid

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