RCN1 Antibody
Product Specifications
Background
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca (+2) -binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.
NCBI Gene ID
5954
Swiss Prot
Q15293
Accession Number
Q15293
Host
Rabbit
Reactivity
Human
Immunogen
This RCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-331 amino acids from the C-terminal region of human RCN1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RCN1
NCBI Official Name
Reticulocalbin-1
NCBI Organism
Homo sapiens
Background Reference 01
Favor, J., et al. Genetics 182 (4) :1077-1088 (2009)
Background Reference 02
Hansen, G.A., et al. Mol. Cell. Biochem. 320 (1-2), 25-33 (2009) :
Background Reference 03
Cooper, C.R., et al. J. Cell. Biochem. 104 (6) :2298-2309 (2008)
Background Reference 04
Lim, J., et al. Cell 125 (4) :801-814 (2006)
Other Product Names
Reticulocalbin-1, RCN1, RCN
Tested Applications
WB
Protein ID
2493462
Physical Properties
Liquid
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