ASB3 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.

NCBI Gene ID

10030265251130

Swiss Prot

Q9Y575

Accession Number

Q9Y575

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ASB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human ASB3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ASB3

NCBI Official Name

Ankyrin repeat and SOCS box protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Yang, Q., et al. BMC Med. Genet.SUPPL 1, S12 (2007) Chung, A.S., et al. Mol. Cell. Biol. 25 (11) :4716-4726 (2005) Kile, B.T., et al. Trends Biochem. Sci. 27 (5) :235-241 (2002) Kile, B.T., et al. Mol. Cell. Biol. 21 (18) :6189-6197 (2001) Kile, B.T., et al. Gene 258 (1-2), 31-41 (2000) :