MGAT3 Antibody

Product Specifications

Background

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified.

NCBI Gene ID

4248

Swiss Prot

Q09327

Accession Number

Q09327

Host

Rabbit

Reactivity

Human

Immunogen

This MGAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-454 amino acids from the C-terminal region of human MGAT3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MGAT3

NCBI Official Name

Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Benson, V., et al. Int. Immunol. 22 (3) :167-177 (2010)

Background Reference 02

Akasaka-Manya, K., et al. Glycobiology 20 (1) :99-106 (2010)

Background Reference 03

Pinho, S.S., et al. Hum. Mol. Genet. 18 (14) :2599-2608 (2009)

Background Reference 04

Sato, Y., et al. J. Biol. Chem. 284 (18) :11873-11881 (2009)

Other Product Names

Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III, GNT-III, GlcNAc-T III, N-acetylglucosaminyltransferase III, MGAT3, GGNT3