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CLK2 Antibody

Product Specifications

Background

This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. Note that this gene is distinct from TELO2 gene (GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common with this gene, but encodes a protein that is involved in telomere length regulation.

NCBI Gene ID

1196

Swiss Prot

P49760

Accession Number

P49760

Host

Rabbit

Reactivity

Human

Immunogen

This CLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the Central region of human CLK2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CLK2

NCBI Official Name

Dual specificity protein kinase CLK2

NCBI Organism

Homo sapiens

Background Reference 01

Nam, S.Y., et al. J. Biol. Chem. 285 (41) :31157-31163 (2010)

Background Reference 02

Eisenreich, A., et al. Circ. Res. 104 (5) :589-599 (2009)

Background Reference 03

Rendtlew Danielsen, J.M., et al. J. Biol. Chem. 284 (7) :4140-4147 (2009)

Background Reference 04

Castle, J.C., et al. Nat. Genet. 40 (12) :1416-1425 (2008)

Other Product Names

Dual specificity protein kinase CLK2, CDC-like kinase 2, CLK2

Tested Applications

WB

Protein ID

1705919

Physical Properties

Liquid

Frequently Asked Questions

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