CPT1B Antibody

Product Specifications

Background

The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.

NCBI Gene ID

1375

Swiss Prot

Q92523

Accession Number

Q92523

Host

Rabbit

Reactivity

Human

Immunogen

This CPT1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-770 amino acids from the C-terminal region of human CPT1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

88 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CPT1B

NCBI Official Name

Carnitine O-palmitoyltransferase 1, muscle isoform

NCBI Organism

Homo sapiens

Background Reference 01

Matsuo, T., et al. Biochem. Genet. 48 (3-4), 193-201 (2010) :

Background Reference 02

Miljkovic, I., et al. Obesity (Silver Spring) 17 (7) :1396-1401 (2009)

Background Reference 03

Miyagawa, T., et al. PLoS ONE (4), E5394 (2009) :

Background Reference 04

Van der Leij, F.R., et al. J. Biol. Chem. 277 (30) :26994-27005 (2002)

Other Product Names

Carnitine O-palmitoyltransferase 1, muscle isoform, CPT1-M, Carnitine O-palmitoyltransferase I, muscle isoform, CPT I, CPTI-M, Carnitine palmitoyltransferase 1B, Carnitine palmitoyltransferase I-like protein, CPT1B, KIAA1670