SNX15 Antibody
Product Specifications
Background
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms. [provided by RefSeq].
NCBI Gene ID
29907
Swiss Prot
Q9NRS6
Accession Number
Q9NRS6
Host
Rabbit
Reactivity
Human
Immunogen
This SNX15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the C-terminal region of human SNX15.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-666
Calculated Molecular Weight
38 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SNX15
NCBI Official Name
Sorting nexin-15
NCBI Organism
Homo sapiens
Background Reference 01
Venter, J.C., et al. Science 291 (5507) :1304-1351 (2001)
Background Reference 02
Phillips, S.A., et al. J. Biol. Chem. 276 (7) :5074-5084 (2001)
Background Reference 03
Barr, V.A., et al. Traffic 1 (11) :904-916 (2000)
Other Product Names
Sorting nexin-15, SNX15
Tested Applications
WB
Protein ID
13124562
Physical Properties
Liquid
Curated Selection
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