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HECW2 Antibody

Product Specifications

Background

E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.

NCBI Gene ID

57520

Swiss Prot

Q9P2P5

Accession Number

Q9P2P5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This HECW2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 848-876 amino acids from the Central region of human HECW2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

176 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HECW2

NCBI Official Name

E3 ubiquitin-protein ligase HECW2

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Miyazaki, K., et al. Biochem. Biophys. Res. Commun. 308 (1) :106-113 (2003)

Other Product Names

E3 ubiquitin-protein ligase HECW2, 632-, HECT, C2 and WW domain-containing protein 2, NEDD4-like E3 ubiquitin-protein ligase 2, HECW2, KIAA1301, NEDL2

Tested Applications

WB

Protein ID

126215718

Physical Properties

Liquid

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