CCNG2 Antibody
Product Specifications
Background
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.
NCBI Gene ID
901
Swiss Prot
Q16589
Accession Number
Q16589
Host
Rabbit
Reactivity
Human
Immunogen
This CCNG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the Central region of human CCNG2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-656
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CCNG2
NCBI Official Name
Cyclin-G2
NCBI Organism
Homo sapiens
Background Reference 01
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 02
Choi, M.G., et al. J. Surg. Res. 157 (2) :168-174 (2009)
Background Reference 03
Cunningham, J.M., et al. Br. J. Cancer 101 (8) :1461-1468 (2009)
Background Reference 04
Xu, G., et al. Mol. Biol. Cell 19 (11) :4968-4979 (2008)
Other Product Names
Cyclin-G2, CCNG2
Tested Applications
WB
Protein ID
9087132
Physical Properties
Liquid
Curated Selection
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