ATP5G1 Antibody
Product Specifications
Background
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8) . This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified.
NCBI Gene ID
516
Swiss Prot
P05496
Accession Number
P05496
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ATP5G1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-56 amino acids from the Central region of human ATP5G1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-646
Calculated Molecular Weight
14 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ATP5G1
NCBI Official Name
ATP synthase F (0) complex subunit C1, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Vives-Bauza, C., et al. Mol. Biol. Cell 21 (1) :131-139 (2010)
Background Reference 02
Wang, H.L., et al. Cytogenet. Genome Res. 109 (4), 533 (2005) :
Background Reference 03
Cross, R.L. Nature 427 (6973) :407-408 (2004)
Background Reference 04
Simpson, J.C., et al. EMBO Rep. 1 (3) :287-292 (2000)
Other Product Names
ATP synthase F (0) complex subunit C1, mitochondrial, ATP synthase lipid-binding protein, ATP synthase proteolipid P1, ATP synthase proton-transporting mitochondrial F (0) complex subunit C1, ATPase protein 9, ATPase subunit c, ATP5G1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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