KCNC4 Antibody

Product Specifications

Background

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene.

NCBI Gene ID

3749

Swiss Prot

Q03721

Accession Number

Q03721

Host

Rabbit

Reactivity

Human

Immunogen

This KCNC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human KCNC4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KCNC4

NCBI Official Name

Potassium voltage-gated channel subfamily C member 4

NCBI Organism

Homo sapiens

Background Reference 01

Mosing, M.A., et al. Twin Res Hum Genet 13 (4) :398-403 (2010)

Background Reference 02

Menendez, S.T., et al. J. Pathol. 221 (4) :402-410 (2010)

Background Reference 03

Leblanc, N. Cardiovasc. Res. 86 (3) :351-352 (2010)

Background Reference 04

Miguel-Velado, E., et al. Cardiovasc. Res. 86 (3) :383-391 (2010)

Other Product Names

Potassium voltage-gated channel subfamily C member 4, KSHIIIC, Voltage-gated potassium channel subunit Kv34, KCNC4

Tested Applications

Protein ID

66774206

Physical Properties

Liquid

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