TNIP2 Antibody

Product Specifications

Background

TNIP2 binds to the C-terminal zinc finger domain of A20 (TNFAIP3; MIM 191163) and is involved in activation of the ERK (see MAPK3; MIM 601795) MAP kinase pathway in various cell types (Van Huffel et al., 2001 [PubMed 11390377]; Papoutsopoulou et al., 2006 [PubMed 16633345]) .

NCBI Gene ID

79155

Swiss Prot

Q8NFZ5

Accession Number

Q8NFZ5

Host

Rabbit

Reactivity

Human

Immunogen

This TNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 amino acids from the Central region of human TNIP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TNIP2

NCBI Official Name

TNFAIP3-interacting protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Raychaudhuri, S., et al. Nat. Genet. 41 (12) :1313-1318 (2009)

Background Reference 02

Handoyo, H., et al. Biochem. J. 424 (1) :109-118 (2009)

Background Reference 03

Verstrepen, L., et al. Biochem. Pharmacol. 78 (2) :105-114 (2009)

Background Reference 04

Huang, L., et al. Oncogene 27 (47) :6131-6140 (2008)

Other Product Names

TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting protein, TNIP2 {ECO:0000312|EMBL:EAW825141}