PLA2G12A Antibody

Product Specifications

Background

Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]) .

NCBI Gene ID

81579

Swiss Prot

Q9BZM1

Accession Number

Q9BZM1

Host

Rabbit

Reactivity

Human

Immunogen

This PLA2G12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the Central region of human PLA2G12A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

21 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PLA2G12A

NCBI Official Name

Group XIIA secretory phospholipase A2

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Kalsi, G., et al. Hum. Mol. Genet. 19 (12) :2497-2506 (2010)

Background Reference 03

Chen, W., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (16) :7401-7406 (2010)

Background Reference 04

Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)

Other Product Names

Group XIIA secretory phospholipase A2, GXII sPLA2, sPLA2-XII, Phosphatidylcholine 2-acylhydrolase 12A, PLA2G12A, PLA2G12

Tested Applications

Protein ID

20143881

Physical Properties

Liquid

Curated Selection

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