SOX8 Antibody
Product Specifications
Background
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome) .
NCBI Gene ID
30812
Swiss Prot
P57073
Accession Number
P57073
Host
Rabbit
Reactivity
Human
Immunogen
This SOX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the Central region of human SOX8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SOX8
NCBI Official Name
Transcription factor SOX-8
NCBI Organism
Homo sapiens
Background Reference 01
Nonaka, D. Am. J. Clin. Pathol. 131 (5) :731-736 (2009)
Background Reference 02
Hoff, S., et al. J. Comp. Neurol. 509 (4) :356-371 (2008)
Background Reference 03
Wissmuller, S., et al. Nucleic Acids Res. 34 (6) :1735-1744 (2006)
Background Reference 04
Schepers, G., et al. J. Biol. Chem. 278 (30) :28101-28108 (2003)
Other Product Names
Transcription factor SOX-8, SOX8
Tested Applications
WB
Protein ID
10720294
Physical Properties
Liquid
Curated Selection
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