DNALI1 Antibody

Product Specifications

Background

This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS) . Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.

NCBI Gene ID

7802

Swiss Prot

O14645

Accession Number

O14645

Host

Rabbit

Reactivity

Human

Immunogen

This DNALI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the C-terminal region of human DNALI1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

30 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DNALI1

NCBI Official Name

Axonemal dynein light intermediate polypeptide 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 03

Combs, J., et al. Proc. Natl. Acad. Sci. U.S.A. 103 (40) :14883-14888 (2006)

Background Reference 04

Kastury, K., et al. J. Clin. Endocrinol. Metab. 82 (9) :3047-3053 (1997)

Other Product Names

Axonemal dynein light intermediate polypeptide 1, Inner dynein arm light chain, axonemal, hp28, DNALI1

Tested Applications

Physical Properties

Liquid

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