MARCH7 Antibody

Product Specifications

Background

MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]) .

NCBI Gene ID

64844

Swiss Prot

Q9H992

Accession Number

Q9H992

Host

Rabbit

Reactivity

Human

Immunogen

This MARCH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-95 amino acids from the N-terminal region of human MARCH7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

78 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MARCH7

NCBI Official Name

E3 ubiquitin-protein ligase MARCH7

NCBI Organism

Homo sapiens

Background Reference 01

Szigyarto, C.A., et al. J. Histochem. Cytochem. 58 (4) :301-308 (2010)

Background Reference 02

Nathan, J.A., et al. Traffic 9 (7) :1130-1145 (2008)

Background Reference 03

Muthukumarana, P.A., et al. Int. Immunopharmacol. (13-14), 1993-2001 (2006) :

Background Reference 04

Flierman, D., et al. Proc. Natl. Acad. Sci. U.S.A. 103 (31) :11589-11594 (2006)

Other Product Names

E3 ubiquitin-protein ligase MARCH7, 632-, Axotrophin, Membrane-associated RING finger protein 7, Membrane-associated RING-CH protein VII, MARCH-VII, RING finger protein 177, MARCH7, AXOT, RNF177